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About us
S.No.
Riboswitch Location and Strand
Riboswitch class
Downstream gene location and Strand
Downstream gene name/gene product description
Locus_tag of downstream gene
Single gene/within operon (According to DOOR database)
Operon details (List of genes within operon and their Locus_tag)
Predicted Structure
1
1261479-1261697
(-)
cobalamin
1259066-1261346 (-)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (4) (Cobalamin-independent methionine synthase) (Methionine synthase; vitamin-B12 independent isozyme)
Rv1133c
Single gene
DOOR ID:
1388274
Rv1133c
View Structure
2
1261484-1261702
(-)
cobalamin
1259071-1261351 (-)
RVBD_1133c
RVBD_1133c
Single gene
DOOR ID:
3873480
RVBD_1133c
View Structure
3
309685-309858
(-)
cobalamin
307876-309547 (-)
PPE2
Uncharacterized PPE family protein PPE2
Rv0256c
Operon
DOOR ID:
6946
Rv0254c,
Rv0255c,
Rv0256c
View Structure
4
309685-309858
(-)
cobalamin
307876-309547 (-)
RVBD_0256c
RVBD_0256c
Operon
DOOR ID:
1132092
RVBD_0254c,
RVBD_0255c,
RVBD_0256c
View Structure
5
2075613-2075710
(+)
glycine
2075876-2078702 (+)
gcvB
Probable glycine dehydrogenase (decarboxylating) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))
Rv1832
Operon
DOOR ID:
7308
Rv1830,
Rv1831,
Rv1832
View Structure
6
2075620-2075717
(+)
glycine
2075883-2078709 (+)
RVBD_1832
RVBD_1832
Operon
DOOR ID:
1132465
RVBD_1830,
RVBD_1831,
RVBD_1832
View Structure
7
79201-79291
(-)
glycine
77615-78893 (-)
RVBD_0070c
RVBD_0070c
Operon
DOOR ID:
1132050
RVBD_0069c,
RVBD_0070c
View Structure
8
79204-79294
(-)
glycine
77618-78896 (-)
glyA2
Serine hydroxymethyltransferase 2 (SHM2) (SHMT 2) (Serine methylase 2)
Rv0070c
Operon
DOOR ID:
6909
Rv0069c,
Rv0070c
View Structure
9
3725971-3726090
(+)
SAM-IV
3726126-3727476 (+)
metC
Probable O-acetylhomoserine sulfhydrylase MetC (Homocysteine synthase) (O-acetylhomoserine (Thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase)
Rv3340
Operon
DOOR ID:
7656
Rv3340,
Rv3341,
Rv3342
View Structure
10
3726142-3726261
(+)
SAM-IV
3726297-3727647 (+)
RVBD_3340
RVBD_3340
Operon
DOOR ID:
1132831
RVBD_3340,
RVBD_3341,
RVBD_3342
View Structure
11
501047-501157
(+)
TPP
502166-502373 (+)
thiS
Possible protein ThiS
Rv0416
Operon
DOOR ID:
6980
Rv0415,
Rv0416,
Rv0417
View Structure
12
501050-501160
(+)
TPP
502169-502376 (+)
RVBD_0416
RVBD_0416
Operon
DOOR ID:
1132125
RVBD_0415,
RVBD_0416,
RVBD_0417
View Structure
13
510216-510326
(-)
TPP
507757-508555 (-)
thiD
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)
Rv0422c
Operon
DOOR ID:
6981
Rv0421c,
Rv0422c,
Rv0423c
View Structure
14
510219-510329
(-)
TPP
507760-508558 (-)
RVBD_0422c
RVBD_0422c
Operon
DOOR ID:
1132126
RVBD_0421c,
RVBD_0422c,
RVBD_0423c
View Structure
15
965545-965767
(-)
ydaO-yuaA
964311-965535 (-)
rpfA
Resuscitation-promoting factor RpfA
Rv0867c
Single gene
DOOR ID:
1388190
Rv0867c
View Structure
16
965548-965770
(-)
ydaO-yuaA
964314-965538 (-)
RVBD_0867c
RVBD_0867c
Single gene
DOOR ID:
3873366
RVBD_0867c
View Structure
17
1735509-1735678
(+)
ykoK
1735975-1736212 (+)
Rv1535
Rv1535
Single gene
DOOR ID:
1388394
Rv1535
View Structure
18
1735515-1735684
(+)
ykoK
1735981-1736218 (+)
RVBD_1535
RVBD_1535
Single gene
DOOR ID:
3873631
RVBD_1535
View Structure
19
2047595-2047769
(+)
ykoK
2048071-2048371 (+)
PE20
PE family protein PE20
Rv1806
Operon
DOOR ID:
7303
Rv1806,
Rv1807
View Structure
20
2047602-2047776
(+)
ykoK
2048078-2048378 (+)
RVBD_1806
RVBD_1806
Operon
DOOR ID:
1132460
RVBD_1806,
RVBD_1807
View Structure
Genome:
Mycobacterium tuberculosis H37Rv
(
NC_018143.2
);
Taxonomy:
Actinobacteria
a:21:{i:0;a:19:{i:0;s:5:"S.No.";i:1;s:9:"Genome_ID";i:2;s:11:"Genome_Name";i:3;s:13:"Taxonomy_name";i:4;s:6:"Tax_ID";i:5;s:19:"Riboswitch_Location";i:6;s:17:"Riboswitch_strand";i:7;s:16:"Riboswitch_class";i:8;s:14:"Tandem_Aptamer";i:9;s:24:"Downstream_gene_location";i:10;s:11:"Gene_Strand";i:11;s:20:"Downstream_gene_name";i:12;s:24:"Gene_product_description";i:13;s:9:"Locus_tag";i:14;s:25:"Single_gene/within_operon";i:15;s:9:"Operon_ID";i:16;s:14:"Operon_details";i:17;s:22:"Biological_process[GO]";i:18;s:9:"Structure";}i:1;a:19:{i:0;i:1;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"1261479-1261697";i:6;s:1:"-";i:7;s:9:"cobalamin";i:8;s:0:"";i:9;s:15:"1259066-1261346";i:10;s:1:"-";i:11;s:4:"metE";i:12;s:172:"5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (4) (Cobalamin-independent methionine synthase) (Methionine synthase; vitamin-B12 independent isozyme)";i:13;s:7:"Rv1133c";i:14;s:11:"Single gene";i:15;s:7:"1388274";i:16;s:7:"Rv1133c";i:17;s:65:"growth [GO:0040007]; homocysteine metabolic process [GO:0050667] ";i:18;N;}i:2;a:19:{i:0;i:2;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"1261484-1261702";i:6;s:1:"-";i:7;s:9:"cobalamin";i:8;s:0:"";i:9;s:15:"1259071-1261351";i:10;s:1:"-";i:11;s:10:"RVBD_1133c";i:12;s:0:"";i:13;s:10:"RVBD_1133c";i:14;s:11:"Single gene";i:15;s:7:"3873480";i:16;s:10:"RVBD_1133c";i:17;s:1:" ";i:18;N;}i:3;a:19:{i:0;i:3;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"309685-309858";i:6;s:1:"-";i:7;s:9:"cobalamin";i:8;s:0:"";i:9;s:13:"307876-309547";i:10;s:1:"-";i:11;s:4:"PPE2";i:12;s:39:"Uncharacterized PPE family protein PPE2";i:13;s:7:"Rv0256c";i:14;s:6:"Operon";i:15;s:4:"6946";i:16;s:25:"Rv0254c; Rv0255c; Rv0256c";i:17;s:1:" ";i:18;N;}i:4;a:19:{i:0;i:4;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"309685-309858";i:6;s:1:"-";i:7;s:9:"cobalamin";i:8;s:0:"";i:9;s:13:"307876-309547";i:10;s:1:"-";i:11;s:10:"RVBD_0256c";i:12;s:0:"";i:13;s:10:"RVBD_0256c";i:14;s:6:"Operon";i:15;s:7:"1132092";i:16;s:34:"RVBD_0254c; RVBD_0255c; RVBD_0256c";i:17;s:1:" ";i:18;N;}i:5;a:19:{i:0;i:5;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"2075613-2075710";i:6;s:1:"+";i:7;s:7:"glycine";i:8;s:0:"";i:9;s:15:"2075876-2078702";i:10;s:1:"+";i:11;s:4:"gcvB";i:12;s:160:"Probable glycine dehydrogenase (decarboxylating) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))";i:13;s:6:"Rv1832";i:14;s:6:"Operon";i:15;s:4:"7308";i:16;s:22:"Rv1830; Rv1831; Rv1832";i:17;s:60:"glycine catabolic process [GO:0006546]; growth [GO:0040007] ";i:18;N;}i:6;a:19:{i:0;i:6;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"2075620-2075717";i:6;s:1:"+";i:7;s:7:"glycine";i:8;s:0:"";i:9;s:15:"2075883-2078709";i:10;s:1:"+";i:11;s:9:"RVBD_1832";i:12;s:0:"";i:13;s:9:"RVBD_1832";i:14;s:6:"Operon";i:15;s:7:"1132465";i:16;s:31:"RVBD_1830; RVBD_1831; RVBD_1832";i:17;s:1:" ";i:18;N;}i:7;a:19:{i:0;i:7;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:11:"79201-79291";i:6;s:1:"-";i:7;s:7:"glycine";i:8;s:0:"";i:9;s:11:"77615-78893";i:10;s:1:"-";i:11;s:10:"RVBD_0070c";i:12;s:0:"";i:13;s:10:"RVBD_0070c";i:14;s:6:"Operon";i:15;s:7:"1132050";i:16;s:22:"RVBD_0069c; RVBD_0070c";i:17;s:1:" ";i:18;N;}i:8;a:19:{i:0;i:8;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:11:"79204-79294";i:6;s:1:"-";i:7;s:7:"glycine";i:8;s:0:"";i:9;s:11:"77618-78896";i:10;s:1:"-";i:11;s:5:"glyA2";i:12;s:71:"Serine hydroxymethyltransferase 2 (SHM2) (SHMT 2) (Serine methylase 2) ";i:13;s:7:"Rv0070c";i:14;s:6:"Operon";i:15;s:4:"6909";i:16;s:16:"Rv0069c; Rv0070c";i:17;s:182:"glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine metabolic process [GO:0006563]; tetrahydrofolate interconversion [GO:0035999] ";i:18;N;}i:9;a:19:{i:0;i:9;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"3725971-3726090";i:6;s:1:"+";i:7;s:6:"SAM-IV";i:8;s:0:"";i:9;s:15:"3726126-3727476";i:10;s:1:"+";i:11;s:4:"metC";i:12;s:163:"Probable O-acetylhomoserine sulfhydrylase MetC (Homocysteine synthase) (O-acetylhomoserine (Thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase)";i:13;s:6:"Rv3340";i:14;s:6:"Operon";i:15;s:4:"7656";i:16;s:22:"Rv3340; Rv3341; Rv3342";i:17;s:57:"'de novo' L-methionine biosynthetic process [GO:0071266] ";i:18;N;}i:10;a:19:{i:0;i:10;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"3726142-3726261";i:6;s:1:"+";i:7;s:6:"SAM-IV";i:8;s:0:"";i:9;s:15:"3726297-3727647";i:10;s:1:"+";i:11;s:9:"RVBD_3340";i:12;s:0:"";i:13;s:9:"RVBD_3340";i:14;s:6:"Operon";i:15;s:7:"1132831";i:16;s:31:"RVBD_3340; RVBD_3341; RVBD_3342";i:17;s:1:" ";i:18;N;}i:11;a:19:{i:0;i:11;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"501047-501157";i:6;s:1:"+";i:7;s:3:"TPP";i:8;s:0:"";i:9;s:13:"502166-502373";i:10;s:1:"+";i:11;s:4:"thiS";i:12;s:21:"Possible protein ThiS";i:13;s:6:"Rv0416";i:14;s:6:"Operon";i:15;s:4:"6980";i:16;s:22:"Rv0415; Rv0416; Rv0417";i:17;s:20:"growth [GO:0040007] ";i:18;N;}i:12;a:19:{i:0;i:12;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"501050-501160";i:6;s:1:"+";i:7;s:3:"TPP";i:8;s:0:"";i:9;s:13:"502169-502376";i:10;s:1:"+";i:11;s:9:"RVBD_0416";i:12;s:0:"";i:13;s:9:"RVBD_0416";i:14;s:6:"Operon";i:15;s:7:"1132125";i:16;s:31:"RVBD_0415; RVBD_0416; RVBD_0417";i:17;s:1:" ";i:18;N;}i:13;a:19:{i:0;i:13;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"510216-510326";i:6;s:1:"-";i:7;s:3:"TPP";i:8;s:0:"";i:9;s:13:"507757-508555";i:10;s:1:"-";i:11;s:4:"thiD";i:12;s:196:"Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)";i:13;s:7:"Rv0422c";i:14;s:6:"Operon";i:15;s:4:"6981";i:16;s:25:"Rv0421c; Rv0422c; Rv0423c";i:17;s:120:"growth [GO:0040007]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229] ";i:18;N;}i:14;a:19:{i:0;i:14;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"510219-510329";i:6;s:1:"-";i:7;s:3:"TPP";i:8;s:0:"";i:9;s:13:"507760-508558";i:10;s:1:"-";i:11;s:10:"RVBD_0422c";i:12;s:0:"";i:13;s:10:"RVBD_0422c";i:14;s:6:"Operon";i:15;s:7:"1132126";i:16;s:34:"RVBD_0421c; RVBD_0422c; RVBD_0423c";i:17;s:1:" ";i:18;N;}i:15;a:19:{i:0;i:15;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"965545-965767";i:6;s:1:"-";i:7;s:9:"ydaO-yuaA";i:8;s:0:"";i:9;s:13:"964311-965535";i:10;s:1:"-";i:11;s:4:"rpfA";i:12;s:36:"Resuscitation-promoting factor RpfA ";i:13;s:7:"Rv0867c";i:14;s:11:"Single gene";i:15;s:7:"1388190";i:16;s:7:"Rv0867c";i:17;s:128:"negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of growth rate [GO:0040010] ";i:18;N;}i:16;a:19:{i:0;i:16;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"965548-965770";i:6;s:1:"-";i:7;s:9:"ydaO-yuaA";i:8;s:0:"";i:9;s:13:"964314-965538";i:10;s:1:"-";i:11;s:10:"RVBD_0867c";i:12;s:0:"";i:13;s:10:"RVBD_0867c";i:14;s:11:"Single gene";i:15;s:7:"3873366";i:16;s:10:"RVBD_0867c";i:17;s:1:" ";i:18;N;}i:17;a:19:{i:0;i:17;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"1735509-1735678";i:6;s:1:"+";i:7;s:4:"ykoK";i:8;s:0:"";i:9;s:15:"1735975-1736212";i:10;s:1:"+";i:11;s:6:"Rv1535";i:12;s:0:"";i:13;s:6:"Rv1535";i:14;s:11:"Single gene";i:15;s:7:"1388394";i:16;s:6:"Rv1535";i:17;s:1:" ";i:18;N;}i:18;a:19:{i:0;i:18;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"1735515-1735684";i:6;s:1:"+";i:7;s:4:"ykoK";i:8;s:0:"";i:9;s:15:"1735981-1736218";i:10;s:1:"+";i:11;s:9:"RVBD_1535";i:12;s:0:"";i:13;s:9:"RVBD_1535";i:14;s:11:"Single gene";i:15;s:7:"3873631";i:16;s:9:"RVBD_1535";i:17;s:1:" ";i:18;N;}i:19;a:19:{i:0;i:19;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"2047595-2047769";i:6;s:1:"+";i:7;s:4:"ykoK";i:8;s:0:"";i:9;s:15:"2048071-2048371";i:10;s:1:"+";i:11;s:4:"PE20";i:12;s:22:"PE family protein PE20";i:13;s:6:"Rv1806";i:14;s:6:"Operon";i:15;s:4:"7303";i:16;s:14:"Rv1806; Rv1807";i:17;s:1:" ";i:18;N;}i:20;a:19:{i:0;i:20;i:1;s:11:"NC_018143.2";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"2047602-2047776";i:6;s:1:"+";i:7;s:4:"ykoK";i:8;s:0:"";i:9;s:15:"2048078-2048378";i:10;s:1:"+";i:11;s:9:"RVBD_1806";i:12;s:0:"";i:13;s:9:"RVBD_1806";i:14;s:6:"Operon";i:15;s:7:"1132460";i:16;s:20:"RVBD_1806; RVBD_1807";i:17;s:1:" ";i:18;N;}}