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S.No.
Riboswitch Location and Strand
Riboswitch class
Downstream gene location and Strand
Downstream gene name/gene product description
Locus_tag of downstream gene
Single gene/within operon (According to DOOR database)
Operon details (List of genes within operon and their Locus_tag)
Predicted Structure
1
79204-79294
(-)
glycine
77618-78896 (-)
glyA2
Serine hydroxymethyltransferase 2 (SHM2) (SHMT 2) (Serine methylase 2)
Rv0070c
Operon
DOOR ID:
6909
Rv0069c
(sdaA)
,
Rv0070c
(glyA)
View Structure
2
309685-309858
(-)
cobalamin
307876-309547 (-)
PPE2
Uncharacterized PPE family protein PPE2
Rv0256c
Operon
DOOR ID:
6946
Rv0254c
(cobU)
,
Rv0255c
(cobQ1)
,
Rv0256c
(PPE2)
View Structure
3
501047-501157
(+)
TPP
502166-502373 (+)
thiS
Possible protein ThiS
Rv0416
Operon
DOOR ID:
6980
Rv0415
(thiO)
,
Rv0416
(thiS)
,
Rv0417
(thiG)
View Structure
4
510216-510326
(-)
TPP
507757-508555 (-)
thiD
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)
Rv0422c
Operon
DOOR ID:
6981
Rv0421c,
Rv0422c
(thiD)
,
Rv0423c
(thiC)
View Structure
5
965545-965767
(-)
ydaO-yuaA
964311-965535 (-)
rpfA
Resuscitation-promoting factor RpfA
Rv0867c
Single gene
DOOR ID:
1388190
Rv0867c
(rpfA)
View Structure
6
1261479-1261697
(-)
cobalamin
1259066-1261346 (-)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (4) (Cobalamin-independent methionine synthase) (Methionine synthase; vitamin-B12 independent isozyme)
Rv1133c
Single gene
DOOR ID:
1388274
Rv1133c
(metE)
View Structure
7
1735509-1735678
(+)
ykoK
1735975-1736212 (+)
Rv1535
Rv1535
Single gene
DOOR ID:
1388394
Rv1535
View Structure
8
2047595-2047769
(+)
ykoK
2048071-2048371 (+)
PE20
PE family protein PE20
Rv1806
Operon
DOOR ID:
7303
Rv1806
(PE20)
,
Rv1807
(PPE31)
View Structure
9
2075613-2075710
(+)
glycine
2075876-2078702 (+)
gcvB
Probable glycine dehydrogenase (decarboxylating) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))
Rv1832
Operon
DOOR ID:
7308
Rv1830,
Rv1831,
Rv1832
(gcvB)
View Structure
10
3725971-3726090
(+)
SAM-IV
3726126-3727476 (+)
metC
Probable O-acetylhomoserine sulfhydrylase MetC (Homocysteine synthase) (O-acetylhomoserine (Thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase)
Rv3340
Operon
DOOR ID:
7656
Rv3340
(metC)
,
Rv3341
(metX)
,
Rv3342
View Structure
Genome:
Mycobacterium tuberculosis H37Rv
(
NC_000962.3
);
Phylum:
Actinobacteria
a:11:{i:0;a:18:{i:0;s:5:"S.No.";i:1;s:9:"Genome_ID";i:2;s:11:"Genome_Name";i:3;s:13:"Taxonomy_name";i:4;s:6:"Tax_ID";i:5;s:19:"Riboswitch_Location";i:6;s:17:"Riboswitch_strand";i:7;s:16:"Riboswitch_class";i:8;s:14:"Tandem_Aptamer";i:9;s:24:"Downstream_gene_location";i:10;s:11:"Gene_Strand";i:11;s:20:"Downstream_gene_name";i:12;s:24:"Gene_product_description";i:13;s:9:"Locus_tag";i:14;s:25:"Single_gene/within_operon";i:15;s:9:"Operon_ID";i:16;s:14:"Operon_details";i:17;s:22:"Biological_process[GO]";}i:1;a:19:{i:0;i:1;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:11:"79204-79294";i:6;s:1:"-";i:7;s:7:"glycine";i:8;s:0:"";i:9;s:11:"77618-78896";i:10;s:1:"-";i:11;s:5:"glyA2";i:12;s:71:"Serine hydroxymethyltransferase 2 (SHM2) (SHMT 2) (Serine methylase 2) ";i:13;s:7:"Rv0070c";i:14;s:6:"Operon";i:15;s:4:"6909";i:16;s:27:"Rv0069c(sdaA);Rv0070c(glyA)";i:17;s:181:"glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine metabolic process [GO:0006563]; tetrahydrofolate interconversion [GO:0035999]";i:18;s:15:"View Structure ";}i:2;a:19:{i:0;i:2;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"309685-309858";i:6;s:1:"-";i:7;s:9:"cobalamin";i:8;s:0:"";i:9;s:13:"307876-309547";i:10;s:1:"-";i:11;s:4:"PPE2";i:12;s:39:"Uncharacterized PPE family protein PPE2";i:13;s:7:"Rv0256c";i:14;s:6:"Operon";i:15;s:4:"6946";i:16;s:42:"Rv0254c(cobU);Rv0255c(cobQ1);Rv0256c(PPE2)";i:17;s:0:"";i:18;s:15:"View Structure ";}i:3;a:19:{i:0;i:3;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"501047-501157";i:6;s:1:"+";i:7;s:3:"TPP";i:8;s:0:"";i:9;s:13:"502166-502373";i:10;s:1:"+";i:11;s:4:"thiS";i:12;s:21:"Possible protein ThiS";i:13;s:6:"Rv0416";i:14;s:6:"Operon";i:15;s:4:"6980";i:16;s:38:"Rv0415(thiO);Rv0416(thiS);Rv0417(thiG)";i:17;s:19:"growth [GO:0040007]";i:18;s:15:"View Structure ";}i:4;a:19:{i:0;i:4;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"510216-510326";i:6;s:1:"-";i:7;s:3:"TPP";i:8;s:0:"";i:9;s:13:"507757-508555";i:10;s:1:"-";i:11;s:4:"thiD";i:12;s:196:"Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)";i:13;s:7:"Rv0422c";i:14;s:6:"Operon";i:15;s:4:"6981";i:16;s:35:"Rv0421c;Rv0422c(thiD);Rv0423c(thiC)";i:17;s:119:"growth [GO:0040007]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]";i:18;s:15:"View Structure ";}i:5;a:19:{i:0;i:5;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:13:"965545-965767";i:6;s:1:"-";i:7;s:9:"ydaO-yuaA";i:8;s:0:"";i:9;s:13:"964311-965535";i:10;s:1:"-";i:11;s:4:"rpfA";i:12;s:36:"Resuscitation-promoting factor RpfA ";i:13;s:7:"Rv0867c";i:14;s:11:"Single gene";i:15;s:7:"1388190";i:16;s:13:"Rv0867c(rpfA)";i:17;s:127:"negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of growth rate [GO:0040010]";i:18;s:15:"View Structure ";}i:6;a:19:{i:0;i:6;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"1261479-1261697";i:6;s:1:"-";i:7;s:9:"cobalamin";i:8;s:0:"";i:9;s:15:"1259066-1261346";i:10;s:1:"-";i:11;s:4:"metE";i:12;s:172:"5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (4) (Cobalamin-independent methionine synthase) (Methionine synthase; vitamin-B12 independent isozyme)";i:13;s:7:"Rv1133c";i:14;s:11:"Single gene";i:15;s:7:"1388274";i:16;s:13:"Rv1133c(metE)";i:17;s:64:"growth [GO:0040007]; homocysteine metabolic process [GO:0050667]";i:18;s:15:"View Structure ";}i:7;a:19:{i:0;i:7;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"1735509-1735678";i:6;s:1:"+";i:7;s:4:"ykoK";i:8;s:0:"";i:9;s:15:"1735975-1736212";i:10;s:1:"+";i:11;s:6:"Rv1535";i:12;s:0:"";i:13;s:6:"Rv1535";i:14;s:11:"Single gene";i:15;s:7:"1388394";i:16;s:6:"Rv1535";i:17;s:0:"";i:18;s:15:"View Structure ";}i:8;a:19:{i:0;i:8;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"2047595-2047769";i:6;s:1:"+";i:7;s:4:"ykoK";i:8;s:0:"";i:9;s:15:"2048071-2048371";i:10;s:1:"+";i:11;s:4:"PE20";i:12;s:22:"PE family protein PE20";i:13;s:6:"Rv1806";i:14;s:6:"Operon";i:15;s:4:"7303";i:16;s:26:"Rv1806(PE20);Rv1807(PPE31)";i:17;s:0:"";i:18;s:15:"View Structure ";}i:9;a:19:{i:0;i:9;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"2075613-2075710";i:6;s:1:"+";i:7;s:7:"glycine";i:8;s:0:"";i:9;s:15:"2075876-2078702";i:10;s:1:"+";i:11;s:4:"gcvB";i:12;s:160:"Probable glycine dehydrogenase (decarboxylating) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))";i:13;s:6:"Rv1832";i:14;s:6:"Operon";i:15;s:4:"7308";i:16;s:26:"Rv1830;Rv1831;Rv1832(gcvB)";i:17;s:59:"glycine catabolic process [GO:0006546]; growth [GO:0040007]";i:18;s:15:"View Structure ";}i:10;a:19:{i:0;i:10;i:1;s:11:"NC_000962.3";i:2;s:32:"Mycobacterium tuberculosis H37Rv";i:3;s:14:"Actinobacteria";i:4;s:6:"201174";i:5;s:15:"3725971-3726090";i:6;s:1:"+";i:7;s:6:"SAM-IV";i:8;s:0:"";i:9;s:15:"3726126-3727476";i:10;s:1:"+";i:11;s:4:"metC";i:12;s:163:"Probable O-acetylhomoserine sulfhydrylase MetC (Homocysteine synthase) (O-acetylhomoserine (Thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase)";i:13;s:6:"Rv3340";i:14;s:6:"Operon";i:15;s:4:"7656";i:16;s:32:"Rv3340(metC);Rv3341(metX);Rv3342";i:17;s:56:"'de novo' L-methionine biosynthetic process [GO:0071266]";i:18;s:15:"View Structure ";}}